Clethodim

Active IngredientClethodim
ClassificationHerbicide / Agrochemical
Formulation85%TECH,  120g/L EC,240G/L EC 
BiochemistryFatty acid synthesis inhibitor, by inhibition of acetyl CoA carboxylase (ACCase). 
Mode of ActionSystemic herbicide, rapidly absorbed and readily translocated from treated foliage to the root system and growing parts of the plant.
UsagePost-emergence control of annual and perennial grasses, at 60-240 g/ha, in a wide range of broad-leaved crops (including such field crops as soya beans, cotton, flax, sunflowers, alfalfa, peanuts, oilseed rape, sugar beet, tobacco, and potatoes), vegetable crops, trees and vines. To be used with a non-phytotoxic crop oil concentrate. Phytotoxicity Good tolerance in broad-leaved crops.
Mammalian ToxicologyReviews FAO/WHO 86 (see part 2 of the Bibliography).  Oral Acute oral LD50 for male rats 1630, female rats 1360, male mice 2570, female mice 2430 mg/kg.  Skin and eye Acute percutaneous LD50 for rabbits >5000 mg/kg. Moderate skin irritant (rabbits). Not a skin sensitiser (guinea pigs).  Inhalation LC50 (4 h) for rats >3.9 mg/l (total aerosol).  NOEL for mice 30, rats 16, dogs 1 mg/kg daily.  ADI (JMPR) 0.01 mg/kg b.w. [1999]; 0.16 mg/kg (Canada); 0.01 mg/kg (USA).  Toxicity class WHO (a.i.) III (company classification); EPA (formulation) III